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Multi-level characterization of balanced inhibitory-excitatory cortical neuron network derived from human pluripotent stem cells

Generation of neuronal cultures from induced pluripotent stem cells (hiPSCs) serve the studies of human brain disorders. However we lack neuronal networks with balanced excitatory-inhibitory activities, which are suitable for single cell analysis. We generated low-density networks of hPSC-derived GA...

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Detalles Bibliográficos
Autores principales: Nadadhur, Aishwarya G., Emperador Melero, Javier, Meijer, Marieke, Schut, Desiree, Jacobs, Gerbren, Li, Ka Wan, Hjorth, J. J. Johannes, Meredith, Rhiannon M., Toonen, Ruud F., Van Kesteren, Ronald E., Smit, August B., Verhage, Matthijs, Heine, Vivi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460818/
https://www.ncbi.nlm.nih.gov/pubmed/28586384
http://dx.doi.org/10.1371/journal.pone.0178533