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Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system

ErbB (Erythroblastic Leukemia Viral Oncogene Homolog) receptor tyrosine kinases are critical for tissue development and maintenance, and frequently become oncogenic when mutated or overexpressed. In vitro analysis of ErbB receptor kinases can be difficult because of their large size and poor water s...

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Detalles Bibliográficos
Autores principales: Scharadin, Tiffany M., He, Wei, Yiannakou, Yianni, Tomilov, Alexey A., Saldana, Matthew, Cortopassi, Gino A., Carraway, Kermit L., Coleman, Matthew A., Henderson, Paul T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460842/
https://www.ncbi.nlm.nih.gov/pubmed/28586369
http://dx.doi.org/10.1371/journal.pone.0177761