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Multi-scale computational study of the mechanical regulation of cell mitotic rounding in epithelia

Mitotic rounding during cell division is critical for preventing daughter cells from inheriting an abnormal number of chromosomes, a condition that occurs frequently in cancer cells. Cells must significantly expand their apical area and transition from a polygonal to circular apical shape to achieve...

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Detalles Bibliográficos
Autores principales: Nematbakhsh, Ali, Sun, Wenzhao, Brodskiy, Pavel A., Amiri, Aboutaleb, Narciso, Cody, Xu, Zhiliang, Zartman, Jeremiah J., Alber, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460904/
https://www.ncbi.nlm.nih.gov/pubmed/28531187
http://dx.doi.org/10.1371/journal.pcbi.1005533