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Multi-scale computational study of the mechanical regulation of cell mitotic rounding in epithelia
Mitotic rounding during cell division is critical for preventing daughter cells from inheriting an abnormal number of chromosomes, a condition that occurs frequently in cancer cells. Cells must significantly expand their apical area and transition from a polygonal to circular apical shape to achieve...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460904/ https://www.ncbi.nlm.nih.gov/pubmed/28531187 http://dx.doi.org/10.1371/journal.pcbi.1005533 |