Degradation Paradigm of the Gut Hormone, Pancreatic Polypeptide, by Hepatic and Renal Peptidases

Pancreatic polypeptide (PP) is a gut hormone that acts on Y4 receptors to reduce appetite. Obese humans display a reduced postprandial increase in PP and remain fully sensitive to the anorectic effects of exogenous PP. The utility of PP as an anti-obesity treatment is limited by its short circulatin...

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Detalles Bibliográficos
Autores principales: Cuenco, Joyceline, Minnion, James, Tan, Tricia, Scott, Rebecca, Germain, Natacha, Ling, Yiin, Chen, Rong, Ghatei, Mohammad, Bloom, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460925/
https://www.ncbi.nlm.nih.gov/pubmed/28323997
http://dx.doi.org/10.1210/en.2016-1827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460925/
https://www.ncbi.nlm.nih.gov/pubmed/28323997
http://dx.doi.org/10.1210/en.2016-1827

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