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Role of Osteoblast G(i) Signaling in Age-Related Bone Loss in Female Mice

Age-related bone loss is an important risk factor for fractures in the elderly; it results from an imbalance in bone remodeling mainly due to decreased bone formation. We have previously demonstrated that endogenous G protein–coupled receptor (GPCR)-driven G(i) signaling in osteoblasts (Obs) restrai...

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Detalles Bibliográficos
Autores principales: Millard, Susan M., Wang, Liping, Wattanachanya, Lalita, O’Carroll, Dylan, Fields, Aaron J., Pang, Joyce, Kazakia, Galateia, Lotz, Jeffrey C., Nissenson, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460929/
https://www.ncbi.nlm.nih.gov/pubmed/28407060
http://dx.doi.org/10.1210/en.2016-1365