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Tissue-Specific Ablation of the LIF Receptor in the Murine Uterine Epithelium Results in Implantation Failure

The cytokine leukemia inhibitory factor (LIF) is essential for rendering the uterus receptive for blastocyst implantation. In mice, LIF receptor expression (LIFR) is largely restricted to the uterine luminal epithelium (LE). LIF, secreted from the endometrial glands (GEs), binds to the LIFR, activat...

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Detalles Bibliográficos
Autores principales: Cheng, JrGang, Rosario, Gracy, Cohen, Tatiana V., Hu, Jianbo, Stewart, Colin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460932/
https://www.ncbi.nlm.nih.gov/pubmed/28368537
http://dx.doi.org/10.1210/en.2017-00103