Deletion of the Thyroid Hormone–Activating Type 2 Deiodinase Rescues Cone Photoreceptor Degeneration but Not Deafness in Mice Lacking Type 3 Deiodinase

Type 2 deiodinase amplifies and type 3 deiodinase depletes levels of the active form of thyroid hormone, triiodothyronine. Given the opposing activities of these enzymes, we tested the hypothesis that they counteract each other’s developmental functions by investigating whether deletion of type 2 de...

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Detalles Bibliográficos
Autores principales: Ng, Lily, Liu, Hong, St. Germain, Donald L., Hernandez, Arturo, Forrest, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460942/
https://www.ncbi.nlm.nih.gov/pubmed/28324012
http://dx.doi.org/10.1210/en.2017-00055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460942/
https://www.ncbi.nlm.nih.gov/pubmed/28324012
http://dx.doi.org/10.1210/en.2017-00055

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