Isoflurane modulates activation and inactivation gating of the prokaryotic Na(+) channel NaChBac

Voltage-gated Na(+) channels (Na(v)) have emerged as important presynaptic targets for volatile anesthetic (VA) effects on synaptic transmission. However, the detailed biophysical mechanisms by which VAs modulate Na(v) function remain unclear. VAs alter macroscopic activation and inactivation of the...

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Detalles Bibliográficos
Autores principales: Sand, Rheanna M., Gingrich, Kevin J., Macharadze, Tamar, Herold, Karl F., Hemmings, Hugh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460948/
https://www.ncbi.nlm.nih.gov/pubmed/28416648
http://dx.doi.org/10.1085/jgp.201611600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460948/
https://www.ncbi.nlm.nih.gov/pubmed/28416648
http://dx.doi.org/10.1085/jgp.201611600

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