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Divergent roles of a peripheral transmembrane segment in AMPA and NMDA receptors

Ionotropic glutamate receptors (iGluRs), including AMPA receptor (AMPAR) and NMDA receptor (NMDAR) subtypes, are ligand-gated ion channels that mediate signaling at the majority of excitatory synapses in the nervous system. The iGluR pore domain is structurally and evolutionarily related to an inver...

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Detalles Bibliográficos
Autores principales: Amin, Johansen B., Salussolia, Catherine L., Chan, Kelvin, Regan, Michael C., Dai, Jian, Zhou, Huan-Xiang, Furukawa, Hiro, Bowen, Mark E., Wollmuth, Lonnie P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460951/
https://www.ncbi.nlm.nih.gov/pubmed/28507080
http://dx.doi.org/10.1085/jgp.201711762