Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice

Cancer cells often acquire capabilities to evade cell death induced by current chemotherapeutic treatment approaches. Caspase-8, a central initiator of death receptor–mediated apoptosis, for example, is frequently inactivated in human cancers via multiple mechanisms such as mutation. Here, we show a...

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Detalles Bibliográficos
Autores principales: He, Gui-Wei, Günther, Claudia, Thonn, Veronika, Yu, Yu-Qiang, Martini, Eva, Buchen, Barbara, Neurath, Markus F., Stürzl, Michael, Becker, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460989/
https://www.ncbi.nlm.nih.gov/pubmed/28476895
http://dx.doi.org/10.1084/jem.20160442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460989/
https://www.ncbi.nlm.nih.gov/pubmed/28476895
http://dx.doi.org/10.1084/jem.20160442

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