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A transit-amplifying population underpins the efficient regenerative capacity of the testis

The spermatogonial stem cell (SSC) that supports spermatogenesis throughout adult life resides within the GFRα1-expressing A type undifferentiated spermatogonia. The decision to commit to spermatogenic differentiation coincides with the loss of GFRα1 and reciprocal gain of Ngn3 (Neurog3) expression....

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Detalles Bibliográficos
Autores principales: Carrieri, Claudia, Comazzetto, Stefano, Grover, Amit, Morgan, Marcos, Buness, Andreas, Nerlov, Claus, O’Carroll, Dónal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460999/
https://www.ncbi.nlm.nih.gov/pubmed/28461596
http://dx.doi.org/10.1084/jem.20161371