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A transit-amplifying population underpins the efficient regenerative capacity of the testis
The spermatogonial stem cell (SSC) that supports spermatogenesis throughout adult life resides within the GFRα1-expressing A type undifferentiated spermatogonia. The decision to commit to spermatogenic differentiation coincides with the loss of GFRα1 and reciprocal gain of Ngn3 (Neurog3) expression....
Autores principales: | Carrieri, Claudia, Comazzetto, Stefano, Grover, Amit, Morgan, Marcos, Buness, Andreas, Nerlov, Claus, O’Carroll, Dónal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460999/ https://www.ncbi.nlm.nih.gov/pubmed/28461596 http://dx.doi.org/10.1084/jem.20161371 |
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