Androgen signaling negatively controls group 2 innate lymphoid cells

Prevalence of asthma is higher in women than in men, but the mechanisms underlying this sex bias are unknown. Group 2 innate lymphoid cells (ILC2s) are key regulators of type 2 inflammatory responses. Here, we show that ILC2 development is greatly influenced by male sex hormones. Male mice have redu...

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Detalles Bibliográficos
Autores principales: Laffont, Sophie, Blanquart, Eve, Savignac, Magali, Cénac, Claire, Laverny, Gilles, Metzger, Daniel, Girard, Jean-Philippe, Belz, Gabrielle T., Pelletier, Lucette, Seillet, Cyril, Guéry, Jean-Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461006/
https://www.ncbi.nlm.nih.gov/pubmed/28484078
http://dx.doi.org/10.1084/jem.20161807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461006/
https://www.ncbi.nlm.nih.gov/pubmed/28484078
http://dx.doi.org/10.1084/jem.20161807

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