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IL-2(high) tissue-resident T cells in the human liver: Sentinels for hepatotropic infection

The liver provides a tolerogenic immune niche exploited by several highly prevalent pathogens as well as by primary and metastatic tumors. We have sampled healthy and hepatitis B virus (HBV)–infected human livers to probe for a subset of T cells specialized to overcome local constraints and mediate...

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Detalles Bibliográficos
Autores principales: Pallett, Laura J., Davies, Jessica, Colbeck, Emily J., Robertson, Francis, Hansi, Navjyot, Easom, Nicholas J.W., Burton, Alice R., Stegmann, Kerstin A., Schurich, Anna, Swadling, Leo, Gill, Upkar S., Male, Victoria, Luong, TuVinh, Gander, Amir, Davidson, Brian R., Kennedy, Patrick T.F., Maini, Mala K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461007/
https://www.ncbi.nlm.nih.gov/pubmed/28526759
http://dx.doi.org/10.1084/jem.20162115