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RNF8 mediates histone H3 ubiquitylation and promotes glycolysis and tumorigenesis

Disassembly of nucleosomes in which genomic DNA is packaged with histone regulates gene expression. However, the mechanisms underlying nucleosome disassembly for gene expression remain elusive. We show here that epidermal growth factor receptor activation results in the binding of the RNF8 forkhead-...

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Detalles Bibliográficos
Autores principales: Xia, Yan, Yang, Weiwei, Fa, Ming, Li, Xinjian, Wang, Yugang, Jiang, Yuhui, Zheng, Yanhua, Lee, Jong-Ho, Li, Jing, Lu, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461008/
https://www.ncbi.nlm.nih.gov/pubmed/28507061
http://dx.doi.org/10.1084/jem.20170015