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Immune checkpoints on innate lymphoid cells

In this issue of JEM, Taylor et al. (https://doi.org/10.1084/jem.20161653) describe PD-1 as a critical negative regulator of group 2 innate lymphoid cells (ILC-2s). PD-1 intrinsically controls proliferation and cytokine production of both mouse and human ILC-2s. PD-1 signaling inhibits STAT5 phospho...

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Detalles Bibliográficos
Autores principales: Chiossone, Laura, Vivier, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461009/
https://www.ncbi.nlm.nih.gov/pubmed/28515074
http://dx.doi.org/10.1084/jem.20170763