Cargando…

Congressing kinetochores progressively load Ska complexes to prevent force-dependent detachment

Kinetochores mediate chromosome congression by either sliding along the lattice of spindle microtubules or forming end-on attachments to their depolymerizing plus-ends. By following the fates of individual kinetochores as they congress in live cells, we reveal that the Ska complex is required for a...

Descripción completa

Detalles Bibliográficos
Autores principales: Auckland, Philip, Clarke, Nicholas I., Royle, Stephen J., McAinsh, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461014/
https://www.ncbi.nlm.nih.gov/pubmed/28495837
http://dx.doi.org/10.1083/jcb.201607096