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UPR transducer BBF2H7 allows export of type II collagen in a cargo- and developmental stage–specific manner

The unfolded protein response (UPR) handles unfolded/misfolded proteins accumulated in the endoplasmic reticulum (ER). However, it is unclear how vertebrates correctly use the total of ten UPR transducers. We have found that ER stress occurs physiologically during early embryonic development in meda...

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Detalles Bibliográficos
Autores principales: Ishikawa, Tokiro, Toyama, Takuya, Nakamura, Yuki, Tamada, Kentaro, Shimizu, Hitomi, Ninagawa, Satoshi, Okada, Tetsuya, Kamei, Yasuhiro, Ishikawa-Fujiwara, Tomoko, Todo, Takeshi, Aoyama, Eriko, Takigawa, Masaharu, Harada, Akihiro, Mori, Kazutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461018/
https://www.ncbi.nlm.nih.gov/pubmed/28500182
http://dx.doi.org/10.1083/jcb.201609100