Spindle assembly checkpoint satisfaction occurs via end-on but not lateral attachments under tension

To ensure accurate chromosome segregation, the spindle assembly checkpoint (SAC) prevents anaphase until all kinetochores attach to the spindle. What signals the SAC monitors remains unclear. We do not know the contributions of different microtubule attachment features or tension from biorientation...

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Detalles Bibliográficos
Autores principales: Kuhn, Jonathan, Dumont, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461026/
https://www.ncbi.nlm.nih.gov/pubmed/28536121
http://dx.doi.org/10.1083/jcb.201611104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461026/
https://www.ncbi.nlm.nih.gov/pubmed/28536121
http://dx.doi.org/10.1083/jcb.201611104

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