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Spindle assembly checkpoint satisfaction occurs via end-on but not lateral attachments under tension
To ensure accurate chromosome segregation, the spindle assembly checkpoint (SAC) prevents anaphase until all kinetochores attach to the spindle. What signals the SAC monitors remains unclear. We do not know the contributions of different microtubule attachment features or tension from biorientation...
Autores principales: | Kuhn, Jonathan, Dumont, Sophie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461026/ https://www.ncbi.nlm.nih.gov/pubmed/28536121 http://dx.doi.org/10.1083/jcb.201611104 |
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