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Oncogene-inducible organoids as a miniature platform to assess cancer characteristics

Direct effects of oncogenic proteins or inhibitor treatments on signaling pathways are difficult to assess in transgenic mice. In this issue, Riemer et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201610058) demonstrate that oncogene-inducible organoids offer the experimental versatility of...

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Detalles Bibliográficos
Autores principales: Mizutani, Tomohiro, Tsukamoto, Yoshiyuki, Clevers, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461034/
https://www.ncbi.nlm.nih.gov/pubmed/28512141
http://dx.doi.org/10.1083/jcb.201704014