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Oncogene-inducible organoids as a miniature platform to assess cancer characteristics
Direct effects of oncogenic proteins or inhibitor treatments on signaling pathways are difficult to assess in transgenic mice. In this issue, Riemer et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201610058) demonstrate that oncogene-inducible organoids offer the experimental versatility of...
Autores principales: | Mizutani, Tomohiro, Tsukamoto, Yoshiyuki, Clevers, Hans |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461034/ https://www.ncbi.nlm.nih.gov/pubmed/28512141 http://dx.doi.org/10.1083/jcb.201704014 |
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