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Suppression of murine tumour growth through CD8(+) cytotoxic T lymphocytes via activated DEC‐205(+) dendritic cells by sequential administration of α‐galactosylceramide in vivo

Cancer immunity is mediated through the effective priming and activation of tumour‐specific class I MHC molecule‐restricted CD8(+) cytotoxic T lymphocytes (CTLs). DEC‐205(+) dendritic cells (DCs) can cross‐present the epitope(s) of captured tumour antigens associated with class I MHC molecules along...

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Detalles Bibliográficos
Autores principales: Kogo, Hideki, Shimizu, Masumi, Negishi, Yasuyuki, Uchida, Eiji, Takahashi, Hidemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461099/
https://www.ncbi.nlm.nih.gov/pubmed/28294313
http://dx.doi.org/10.1111/imm.12733