Cargando…

Ageing adversely affects the migration and function of marginal zone B cells

Marginal zone (MZ) B cells are positioned within the spleen to capture blood‐borne antigen and immune complexes and deliver them to follicular dendritic cells in the B‐cell follicles. We show that within the spleens of aged mice antigen capture by MZ B cells, and their ability to shuttle between the...

Descripción completa

Detalles Bibliográficos
Autores principales: Turner, Vivian M., Mabbott, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461100/
https://www.ncbi.nlm.nih.gov/pubmed/28369800
http://dx.doi.org/10.1111/imm.12737