Inter-Fork Strand Annealing causes genomic deletions during the termination of DNA replication

Problems that arise during DNA replication can drive genomic alterations that are instrumental in the development of cancers and many human genetic disorders. Replication fork barriers are a commonly encountered problem, which can cause fork collapse and act as hotspots for replication termination....

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Detalles Bibliográficos
Autores principales: Morrow, Carl A, Nguyen, Michael O, Fower, Andrew, Wong, Io Nam, Osman, Fekret, Bryer, Claire, Whitby, Matthew C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461108/
https://www.ncbi.nlm.nih.gov/pubmed/28586299
http://dx.doi.org/10.7554/eLife.25490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461108/
https://www.ncbi.nlm.nih.gov/pubmed/28586299
http://dx.doi.org/10.7554/eLife.25490

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