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The step-wise pathway of septin hetero-octamer assembly in budding yeast

Septin proteins bind guanine nucleotides and form rod-shaped hetero-oligomers. Cells choose from a variety of available septins to assemble distinct hetero-oligomers, but the underlying mechanism was unknown. Using a new in vivo assay, we find that a stepwise assembly pathway produces the two specie...

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Detalles Bibliográficos
Autores principales: Weems, Andrew, McMurray, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461111/
https://www.ncbi.nlm.nih.gov/pubmed/28541184
http://dx.doi.org/10.7554/eLife.23689