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Non-canonical Glucocorticoid Receptor Transactivation of gilz by Alcohol Suppresses Cell Inflammatory Response

Acute alcohol exposure suppresses cell inflammatory response. The underlying mechanism has not been fully defined. Here we report that alcohol was able to activate glucocorticoid receptor (GR) signaling in the absence of glucocorticoids (GCs) and upregulated glucocorticoid-induced leucine zipper (gi...

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Detalles Bibliográficos
Autores principales: Ng, Hang Pong, Jennings, Scott, Wang, Jack, Molina, Patricia E., Nelson, Steve, Wang, Guoshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461336/
https://www.ncbi.nlm.nih.gov/pubmed/28638383
http://dx.doi.org/10.3389/fimmu.2017.00661