Cargando…

Non-canonical Glucocorticoid Receptor Transactivation of gilz by Alcohol Suppresses Cell Inflammatory Response

Acute alcohol exposure suppresses cell inflammatory response. The underlying mechanism has not been fully defined. Here we report that alcohol was able to activate glucocorticoid receptor (GR) signaling in the absence of glucocorticoids (GCs) and upregulated glucocorticoid-induced leucine zipper (gi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ng, Hang Pong, Jennings, Scott, Wang, Jack, Molina, Patricia E., Nelson, Steve, Wang, Guoshun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461336/ https://www.ncbi.nlm.nih.gov/pubmed/28638383 http://dx.doi.org/10.3389/fimmu.2017.00661

Ejemplares similares

Short-Chain Alcohols Upregulate GILZ Gene Expression and Attenuate LPS-Induced Septic Immune Response
por: Ng, Hang Pong, et al.
Publicado: (2020)

Corrigendum: Short-Chain Alcohols Upregulate GILZ Gene Expression and Attenuate LPS-Induced Septic Immune Response
por: Ng, Hang Pong, et al.
Publicado: (2022)

Glucocorticoids and Glucocorticoid-Induced-Leucine-Zipper (GILZ) in Psoriasis
por: Sevilla, Lisa M., et al.
Publicado: (2019)

Type 1 interferon suppresses expression and glucocorticoid induction of glucocorticoid-induced leucine zipper (GILZ)
por: Dankers, Wendy, et al.
Publicado: (2022)

Could GILZ Be the Answer to Glucocorticoid Toxicity in Lupus?
por: Flynn, Jacqueline K., et al.
Publicado: (2019)

Implicating the Role of GILZ in Glucocorticoid Modulation of T-Cell Activation
por: Cannarile, Lorenza, et al.
Publicado: (2019)

GILZ as a Mediator of the Anti-Inflammatory Effects of Glucocorticoids
por: Ronchetti, Simona, et al.
Publicado: (2015)

Amplified Host Defense by Toll-Like Receptor-Mediated Downregulation of the Glucocorticoid-Induced Leucine Zipper (GILZ) in Macrophages
por: Hoppstädter, Jessica, et al.
Publicado: (2019)

Glucocorticoid-induced leucine zipper (GILZ) in immuno suppression: master regulator or bystander?
por: Hoppstädter, Jessica, et al.
Publicado: (2015)

Development of novel treatment strategies for inflammatory diseases—similarities and divergence between glucocorticoids and GILZ
por: Cheng, Qiang, et al.
Publicado: (2014)

Role of glucocorticoid-induced leucine zipper (GILZ) in inflammatory bone loss
por: Yang, Nianlan, et al.
Publicado: (2017)

Glucocorticoid-Induced Leucine Zipper (GILZ) in Cardiovascular Health and Disease
por: Cappetta, Donato, et al.
Publicado: (2021)

Glucocorticoid-induced leucine zipper (GILZ)/NF-κB interaction: role of GILZ homo-dimerization and C-terminal domain
por: Marco, Barbara Di, et al.
Publicado: (2007)

Commentary: Short-Chain Alcohols Upregulate GILZ Gene Expression and Attenuate LPS-Induced Septic Immune Response
por: Pál, László, et al.
Publicado: (2020)

Expression of concern on ‘glucocorticoid-induced leucine zipper (GILZ)/NF-κB interaction: role of GILZ homo-dimerization and C-terminal domain’
Publicado: (2022)

Editor's Note on ‘Glucocorticoid-induced leucine zipper (GILZ)/NF-κB interaction: role of GILZ homo-dimerization and C-terminal domain’
Publicado: (2023)

GILZ Regulates the Expression of Pro-Inflammatory Cytokines and Protects Against End-Organ Damage in a Model of Lupus
por: Nataraja, Champa, et al.
Publicado: (2021)

Glucocorticoid-induced leucine zipper (GILZ) is involved in glucocorticoid-induced and mineralocorticoid-induced leptin production by osteoarthritis synovial fibroblasts
por: Malaise, Olivier, et al.
Publicado: (2016)

Dexamethasone Inhibits Repair of Human Airway Epithelial Cells Mediated by Glucocorticoid-Induced Leucine Zipper (GILZ)
por: Liu, Jingyue, et al.
Publicado: (2013)

Quantitative tissue-specific dynamics of in vivo GILZ mRNA expression and regulation by endogenous and exogenous glucocorticoids
por: Ayyar, Vivaswath S, et al.
Publicado: (2015)

Anti-Inflammatory Effects of Synthetic Peptides Based on Glucocorticoid-Induced Leucine Zipper (GILZ) Protein for the Treatment of Inflammatory Bowel Diseases (IBDs)
por: Paglialunga, Musetta, et al.
Publicado: (2023)

Neutrophil expression of glucocorticoid-induced leucine zipper (GILZ) anti-inflammatory protein is associated with acute respiratory distress syndrome severity
por: Espinasse, Marie-Alix, et al.
Publicado: (2016)

Glucocorticoid Receptor Transactivation Is Required for Glucocorticoid-Induced Ocular Hypertension and Glaucoma
por: Patel, Gaurang C., et al.
Publicado: (2019)

Glucocorticoid-Induced Leucine Zipper (GILZ) Antagonizes TNF-α Inhibition of Mesenchymal Stem Cell Osteogenic Differentiation
por: He, Linlin, et al.
Publicado: (2012)

Loss of CFTR function in macrophages alters the cell transcriptional program and delays lung resolution of inflammation
por: Wellems, Dianne, et al.
Publicado: (2023)

Role of histamine H(4) receptor in the anti-inflammatory pathway of glucocorticoid-induced leucin zipper (GILZ) in a model of lung fibrosis
por: Sgambellone, Silvia, et al.
Publicado: (2023)

The C-Terminal Transactivation Domain of STAT1 Has a Gene-Specific Role in Transactivation and Cofactor Recruitment
por: Parrini, Matthias, et al.
Publicado: (2018)

Glucocorticoid-Induced Leucine Zipper (GILZ) Regulates Testicular FOXO1 Activity and Spermatogonial Stem Cell (SSC) Function
por: Ngo, Devi, et al.
Publicado: (2013)

GILZ as a Regulator of Cell Fate and Inflammation
por: Bruscoli, Stefano, et al.
Publicado: (2021)

Respiratory syncytial virus (RSV) suppression of glucocorticoid receptor phosphorylation does not account for repression of transactivation()
por: Webster Marketon, Jeanette I., et al.
Publicado: (2013)

More Than Suppression: Glucocorticoid Action on Monocytes and Macrophages
por: Ehrchen, Jan M., et al.
Publicado: (2019)

Wanted: A New Model for Glucocorticoid Receptor Transactivation and Transrepression
por: Sedwick, Caitlin
Publicado: (2014)

Overexpression of Glucocorticoid-induced Leucine Zipper (GILZ) increases susceptibility to Imiquimod-induced psoriasis and involves cutaneous activation of TGF-β1
por: Carceller, Elena, et al.
Publicado: (2016)

Bcl-xL overexpression decreases GILZ levels and inhibits glucocorticoid-induced activation of caspase-8 and caspase-3 in mouse thymocytes
por: Muscari, Isabella, et al.
Publicado: (2020)

Association of GILZ with MUC2, TLR2, and TLR4 in Inflammatory Bowel Disease
por: Cari, Luigi, et al.
Publicado: (2023)

Glucocorticoid Repression of Inflammatory Gene Expression Shows Differential Responsiveness by Transactivation- and Transrepression-Dependent Mechanisms
por: King, Elizabeth M., et al.
Publicado: (2013)

Endothelial Response to Glucocorticoids in Inflammatory Diseases
por: Zielińska, Karolina A., et al.
Publicado: (2016)

Editorial: Regulatory T Cell Heterogeneity: Canonical and Non-Canonical Functions
por: Sefik, Esen, et al.
Publicado: (2021)

Reduced expression of glucocorticoid-inducible genes GILZ and SGK-1: high IL-6 levels are associated with reduced hippocampal volumes in major depressive disorder
por: Frodl, T, et al.
Publicado: (2012)

TLR9 Signaling Suppresses the Canonical Plasma Cell Differentiation Program in Follicular B Cells
por: Baptista, Bárbara José Antunes, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_pjgrlj4s9nadu3f5an50ik1oto