Functional roles of carboxylate residues comprising the DNA polymerase active site triad of Ty3 reverse transcriptase

Aspartic acid residues comprising the -D-(aa)(n)-Y-L-D-D- DNA polymerase active site triad of reverse transcriptase from the Saccharomyces cerevisiae long terminal repeat-retrotransposon Ty3 (Asp151, Asp213 and Asp214) were evaluated via site-directed mutagenesis. An Asp151→Glu substitution showed a...

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Detalles Bibliográficos
Autores principales: Bibillo, Arkadiusz, Lener, Daniela, Klarmann, George J., Le Grice, Stuart F. J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546138/
https://www.ncbi.nlm.nih.gov/pubmed/15647500
http://dx.doi.org/10.1093/nar/gki150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546138/
https://www.ncbi.nlm.nih.gov/pubmed/15647500
http://dx.doi.org/10.1093/nar/gki150

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