Novel Nonreplicating Vaccinia Virus Vector Enhances Expression of Heterologous Genes and Suppresses Synthesis of Endogenous Viral Proteins

Viruses are used as expression vectors for protein synthesis, immunology research, vaccines, and therapeutics. Advantages of poxvirus vectors include the accommodation of large amounts of heterologous DNA, the presence of a cytoplasmic site of transcription, and high expression levels. On the other...

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Detalles Bibliográficos
Autores principales: Wyatt, Linda S., Xiao, Wei, Americo, Jeffrey L., Earl, Patricia L., Moss, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461411/
https://www.ncbi.nlm.nih.gov/pubmed/28588133
http://dx.doi.org/10.1128/mBio.00790-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461411/
https://www.ncbi.nlm.nih.gov/pubmed/28588133
http://dx.doi.org/10.1128/mBio.00790-17

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