Cargando…

Novel Nonreplicating Vaccinia Virus Vector Enhances Expression of Heterologous Genes and Suppresses Synthesis of Endogenous Viral Proteins

Viruses are used as expression vectors for protein synthesis, immunology research, vaccines, and therapeutics. Advantages of poxvirus vectors include the accommodation of large amounts of heterologous DNA, the presence of a cytoplasmic site of transcription, and high expression levels. On the other...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wyatt, Linda S., Xiao, Wei, Americo, Jeffrey L., Earl, Patricia L., Moss, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461411/ https://www.ncbi.nlm.nih.gov/pubmed/28588133 http://dx.doi.org/10.1128/mBio.00790-17

Ejemplares similares

Existence and significance of viral nonreplicative RNA recombination
por: Agol, Vadim I.
Publicado: (2023)

DNA/MVA HIV-1/AIDS vaccine elicits long-lived vaccinia virus-specific immunity and confers protection against a lethal monkeypox challenge
por: Nigam, Pragati, et al.
Publicado: (2007)

Nonreplicating Adenoviral Vectors: Improving Tropism and Delivery of Cancer Gene Therapy
por: Tessarollo, Nayara Gusmão, et al.
Publicado: (2021)

Eagle Effect in Nonreplicating Persister Mycobacteria
por: Wu, Mu-Lu, et al.
Publicado: (2015)

Nonreplicative functions of the origin recognition complex
por: Popova, Varvara V., et al.
Publicado: (2018)

Characterisation of systemic dissemination of nonreplicating adenoviral vectors from tumours in local gene delivery
por: Wang, Y, et al.
Publicado: (2005)

Design and Engineering of Deimmunized Vaccinia Viral Vectors
por: Song, Kevin, et al.
Publicado: (2020)

Crystallization of a nonreplicating rotavirus vaccine candidate
por: Hong, Moo Sun, et al.
Publicado: (2021)

Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis
por: Gold, Ben, et al.
Publicado: (2016)

Fine-tuning levels of heterologous gene expression in plants by orthogonal variation of the untranslated regions of a nonreplicating transient expression system
por: Meshcheriakova, Yulia A, et al.
Publicado: (2014)

Genetic studies of the susceptibility of classical and wild-derived inbred mouse strains to monkeypox virus
por: Earl, Patricia L., et al.
Publicado: (2015)

Natural killer cells expanded in vivo or ex vivo with IL-15 overcomes the inherent susceptibility of CAST mice to lethal infection with orthopoxviruses
por: Earl, Patricia L., et al.
Publicado: (2020)

Virulence differences of mpox (monkeypox) virus clades I, IIa, and IIb.1 in a small animal model
por: Americo, Jeffrey L., et al.
Publicado: (2023)

P19-52 LB. Assessing and restructuring foreign gene insertion sites for enhanced stability of modified Vaccinia virus ankara recombinants expressing HIV genes
por: Wyatt, L, et al.
Publicado: (2009)

Antibiotic Killing of Diversely Generated Populations of Nonreplicating Bacteria
por: McCall, Ingrid C., et al.
Publicado: (2019)

Availability and Accessibility of Live Nonreplicating Smallpox/Mpox Vaccine
por: Kahn, Peter A., et al.
Publicado: (2023)

MVA Vector Vaccines Inhibit SARS CoV-2 Replication in Upper and Lower Respiratory Tracts of Transgenic Mice and Prevent Lethal Disease
por: Liu, Ruikang, et al.
Publicado: (2021)

SPI-1 is a missing host-range factor required for replication of the attenuated modified vaccinia Ankara (MVA) vaccine vector in human cells
por: Liu, Ruikang, et al.
Publicado: (2019)

Comparison of replicating and nonreplicating vaccines against SARS-CoV-2
por: Mudrick, Haley E., et al.
Publicado: (2022)

Nonreplicative RNA Recombination of an Animal Plus-Strand RNA Virus in the Absence of Efficient Translation of Viral Proteins
por: Kleine Büning, Maximiliane, et al.
Publicado: (2017)

Steroid Hormone Synthesis by Vaccinia Virus Suppresses the Inflammatory Response to Infection
por: Reading, Patrick C., et al.
Publicado: (2003)

One or two injections of MVA-vectored vaccine shields hACE2 transgenic mice from SARS-CoV-2 upper and lower respiratory tract infection
por: Liu, Ruikang, et al.
Publicado: (2021)

Engineering the vaccinia virus L1 protein for increased neutralizing antibody response after DNA immunization
por: Shinoda, Kaori, et al.
Publicado: (2009)

Serum neopterin levels in patients with replicative and nonreplicative HBV carriers
por: Kaleli, Ilknur, et al.
Publicado: (2006)

Comparative live bioluminescence imaging of monkeypox virus dissemination in a wild-derived inbred mouse (Mus musculus castaneus) and outbred African dormouse (Graphiurus kelleni)
por: Earl, Patricia L., et al.
Publicado: (2015)

Protection from SARS-CoV-2 Variants by MVAs expressing matched or mismatched S administered intranasally to mice
por: Cotter, Catherine A., et al.
Publicado: (2023)

Pentacyclic Nitrofurans with In Vivo Efficacy and Activity against Nonreplicating Mycobacterium tuberculosis
por: Rakesh,, et al.
Publicado: (2014)

Role of Alanine Dehydrogenase of Mycobacterium tuberculosis during Recovery from Hypoxic Nonreplicating Persistence
por: Giffin, Michelle M., et al.
Publicado: (2016)

Intranasal inoculation of an MVA-based vaccine induces IgA and protects the respiratory tract of hACE2 mice from SARS-CoV-2 infection
por: Americo, Jeffrey L., et al.
Publicado: (2022)

Tedizolid, Faropenem, and Moxifloxacin Combination With Potential Activity Against Nonreplicating Mycobacterium tuberculosis
por: Srivastava, Shashikant, et al.
Publicado: (2021)

Vaccinia Virus: From Crude Smallpox Vaccines to Elaborate Viral Vector Vaccine Design
por: Kaynarcalidan, Onur, et al.
Publicado: (2021)

The Membrane Fusion Step of Vaccinia Virus Entry Is Cooperatively Mediated by Multiple Viral Proteins and Host Cell Components
por: Laliberte, Jason P., et al.
Publicado: (2011)

Interferon α/β Decoy Receptor Encoded by a Variant in the Dryvax Smallpox Vaccine Contributes to Virulence and Correlates with Severe Vaccine Side Effects
por: Liu, Ruikang, et al.
Publicado: (2022)

Nonreplicating Influenza A Virus Vaccines Confer Broad Protection against Lethal Challenge
por: Baz, Mariana, et al.
Publicado: (2015)

Ribosome Rescue Inhibitors Kill Actively Growing and Nonreplicating Persister Mycobacterium tuberculosis Cells
por: Alumasa, John N., et al.
Publicado: (2017)

A heterologous prime-boosting strategy with replicating Vaccinia virus vectors and plant-produced HIV-1 Gag/dgp41 virus-like particles
por: Meador, Lydia R., et al.
Publicado: (2017)

Zinc-finger antiviral protein (ZAP) is a restriction factor for replication of modified vaccinia virus Ankara (MVA) in human cells
por: Peng, Chen, et al.
Publicado: (2020)

Modified Vaccinia Virus Ankara as a Viral Vector for Vaccine Candidates against Chikungunya Virus
por: García-Arriaza, Juan, et al.
Publicado: (2021)

Heterologous Prime-Boost Regimens Using rAd35 and rMVA Vectors Elicit Stronger Cellular Immune Responses to HIV Proteins Than Homologous Regimens
por: Ratto-Kim, Silvia, et al.
Publicado: (2012)

Elimination of A-type inclusion formation enhances cowpox virus replication in mice: Implications for orthopoxvirus evolution
por: Kastenmayer, Robin J., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_se3n3c50td53i4s1ahrgdrvb7j