Effects of camptothecin on double-strand break repair by non-homologous end-joining in DNA mismatch repair-deficient human colorectal cancer cell lines

Loss of a functional mismatch repair (MMR) system in colorectal cancer (CRC) cells is associated with microsatellite instability and increased sensitivity to topoisomerase inhibitors. In this study, we have investigated whether a defect in double-strand break (DSB) repair by non-homologous end-joini...

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Detalles Bibliográficos
Autores principales: Jacob, Sandrine, Miquel, Catherine, Sarasin, Alain, Praz, Françoise
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546142/
https://www.ncbi.nlm.nih.gov/pubmed/15642697
http://dx.doi.org/10.1093/nar/gki154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546142/
https://www.ncbi.nlm.nih.gov/pubmed/15642697
http://dx.doi.org/10.1093/nar/gki154

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