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Analysis of Public Oral Toxicity Data from REACH Registrations 2008–2014

The European Chemicals Agency, ECHA, made available a total of 13,832 oral toxicity studies for 8,568 substances up to December 2014. 75% of studies were from the retired OECD Test Guideline 401 (11% TG 420, 11% TG 423 and 1.5% TG 425). Concordance across guidelines, evaluated by comparing LD(50) va...

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Detalles Bibliográficos
Autores principales: Luechtefeld, Thomas, Maertens, Alexandra, Russo, Daniel P., Rovida, Costanza, Zhu, Hao, Hartung, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461469/
https://www.ncbi.nlm.nih.gov/pubmed/26863198
http://dx.doi.org/10.14573/altex.1510054