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Strength of Neisseria meningitidis binding to endothelial cells requires highly-ordered CD147/β(2)-adrenoceptor clusters assembled by alpha-actinin-4

Neisseria meningitidis (meningococcus) is an invasive bacterial pathogen that colonizes human vessels, causing thrombotic lesions and meningitis. Establishment of tight interactions with endothelial cells is crucial for meningococci to resist haemodynamic forces. Two endothelial receptors, CD147 and...

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Detalles Bibliográficos
Autores principales: Maïssa, Nawal, Covarelli, Valentina, Janel, Sébastien, Durel, Beatrice, Simpson, Nandi, Bernard, Sandra C., Pardo-Lopez, Liliana, Bouzinba-Ségard, Haniaa, Faure, Camille, Scott, Mark G.H., Coureuil, Mathieu, Morand, Philippe C., Lafont, Frank, Nassif, Xavier, Marullo, Stefano, Bourdoulous, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461506/
https://www.ncbi.nlm.nih.gov/pubmed/28569760
http://dx.doi.org/10.1038/ncomms15764