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Comparative study of sequence-dependent hybridization kinetics in solution and on microspheres
Hybridization kinetics of DNA sequences with known secondary structures and random sequences designed with similar melting temperatures were studied in solution and when one strand was bound to 5 μm silica microspheres. The rates of hybridization followed second-order kinetics and were measured spec...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546151/ https://www.ncbi.nlm.nih.gov/pubmed/15653637 http://dx.doi.org/10.1093/nar/gki163 |