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Comparative study of sequence-dependent hybridization kinetics in solution and on microspheres

Hybridization kinetics of DNA sequences with known secondary structures and random sequences designed with similar melting temperatures were studied in solution and when one strand was bound to 5 μm silica microspheres. The rates of hybridization followed second-order kinetics and were measured spec...

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Detalles Bibliográficos
Autores principales: Sekar, Michael M. A., Bloch, Will, St John, Pamela M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546151/
https://www.ncbi.nlm.nih.gov/pubmed/15653637
http://dx.doi.org/10.1093/nar/gki163

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