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Taking promoters out of enhancers in sequence based predictions of tissue-specific mammalian enhancers
BACKGROUND: Many genetic diseases are caused by mutations in non-coding regions of the genome. These mutations are frequently found in enhancer sequences, causing disruption to the regulatory program of the cell. Enhancers are short regulatory sequences in the non-coding part of the genome that are...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461523/ https://www.ncbi.nlm.nih.gov/pubmed/28589862 http://dx.doi.org/10.1186/s12920-017-0264-3 |