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Protease-Inhibitor Interaction Predictions: Lessons on the Complexity of Protein–Protein Interactions

Protein interactions shape proteome function and thus biology. Identification of protein interactions is a major goal in molecular biology, but biochemical methods, although improving, remain limited in coverage and accuracy. Whereas computational predictions can guide biochemical experiments, low v...

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Detalles Bibliográficos
Autores principales: Fortelny, Nikolaus, Butler, Georgina S., Overall, Christopher M., Pavlidis, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461536/
https://www.ncbi.nlm.nih.gov/pubmed/28385878
http://dx.doi.org/10.1074/mcp.M116.065706