Cargando…

mTOR activation is increased in pilocytic astrocytomas from older adults compared with children

BACKGROUND: Recent studies suggest that the behavior and biology of WHO grade I pilocytic astrocytomas (PAs) in adults is different than that associated with grade I PAs in children. METHODS: We evaluated Ki-67 labeling, BRAF abnormalities, isocitrate dehydrogenase R132 immunoreactivity phosphorylat...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnson, Mahlon D., O’Connell, Mary, Walter, Kevin, Silberstein, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461564/
https://www.ncbi.nlm.nih.gov/pubmed/28607819
http://dx.doi.org/10.4103/sni.sni_367_16