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Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d

Sac7d, a small, abundant, sequence-general DNA-binding protein from the hyperthermophilic archaeon Sulfolobus acidocaldarius, causes a single-step sharp kink in DNA (∼60°) via the intercalation of both Val26 and Met29. These two amino acids were systematically changed in size to probe their effects...

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Detalles Bibliográficos
Autores principales: Chen, Chin-Yu, Ko, Tzu-Ping, Lin, Ting-Wan, Chou, Chia-Cheng, Chen, Chun-Jung, Wang, Andrew H.-J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546169/
https://www.ncbi.nlm.nih.gov/pubmed/15653643
http://dx.doi.org/10.1093/nar/gki191