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Probing the DNA kink structure induced by the hyperthermophilic chromosomal protein Sac7d
Sac7d, a small, abundant, sequence-general DNA-binding protein from the hyperthermophilic archaeon Sulfolobus acidocaldarius, causes a single-step sharp kink in DNA (∼60°) via the intercalation of both Val26 and Met29. These two amino acids were systematically changed in size to probe their effects...
Autores principales: | Chen, Chin-Yu, Ko, Tzu-Ping, Lin, Ting-Wan, Chou, Chia-Cheng, Chen, Chun-Jung, Wang, Andrew H.-J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC546169/ https://www.ncbi.nlm.nih.gov/pubmed/15653643 http://dx.doi.org/10.1093/nar/gki191 |
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