Characterization of tau prion seeding activity and strains from formaldehyde-fixed tissue

Tauopathies such as Alzheimer’s disease (AD) feature progressive intraneuronal deposition of aggregated tau protein. The cause is unknown, but in experimental systems trans-cellular propagation of tau pathology resembles prion pathogenesis. Tau aggregate inoculation into mice produces transmissible...

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Detalles Bibliográficos
Autores principales: Kaufman, Sarah K., Thomas, Talitha L., Del Tredici, Kelly, Braak, Heiko, Diamond, Marc I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461712/
https://www.ncbi.nlm.nih.gov/pubmed/28587664
http://dx.doi.org/10.1186/s40478-017-0442-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461712/
https://www.ncbi.nlm.nih.gov/pubmed/28587664
http://dx.doi.org/10.1186/s40478-017-0442-8

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