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Characterization of tau prion seeding activity and strains from formaldehyde-fixed tissue
Tauopathies such as Alzheimer’s disease (AD) feature progressive intraneuronal deposition of aggregated tau protein. The cause is unknown, but in experimental systems trans-cellular propagation of tau pathology resembles prion pathogenesis. Tau aggregate inoculation into mice produces transmissible...
Autores principales: | Kaufman, Sarah K., Thomas, Talitha L., Del Tredici, Kelly, Braak, Heiko, Diamond, Marc I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461712/ https://www.ncbi.nlm.nih.gov/pubmed/28587664 http://dx.doi.org/10.1186/s40478-017-0442-8 |
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