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RNA sequencing and transcriptome arrays analyses show opposing results for alternative splicing in patient derived samples

BACKGROUND: RNA sequencing (RNA-seq) and microarrays are two transcriptomics techniques aimed at the quantification of transcribed genes and their isoforms. Here we compare the latest Affymetrix HTA 2.0 microarray with Illumina 2000 RNA-seq for the analysis of patient samples - normal lung epitheliu...

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Detalles Bibliográficos
Autores principales: Nazarov, Petr V., Muller, Arnaud, Kaoma, Tony, Nicot, Nathalie, Maximo, Cristina, Birembaut, Philippe, Tran, Nhan L., Dittmar, Gunnar, Vallar, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461714/
https://www.ncbi.nlm.nih.gov/pubmed/28587590
http://dx.doi.org/10.1186/s12864-017-3819-y