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The effects of basal insulin peglispro vs. insulin glargine on lipoprotein particles by NMR and liver fat content by MRI in patients with diabetes

BACKGROUND: In Phase 2/3 studies of basal insulin peglispro (BIL) compared to insulin glargine, patients with type 1 or type 2 diabetes previously treated with insulin and randomized to BIL had an increase in serum triglycerides (TGs). To further understand lipoprotein changes, a lipid substudy whic...

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Detalles Bibliográficos
Autores principales: Orchard, Trevor J., Cariou, Bertrand, Connelly, Margery A., Otvos, James D., Zhang, Shuyu, Antalis, Caryl J., Ivanyi, Tibor, Hoogwerf, Byron J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461740/
https://www.ncbi.nlm.nih.gov/pubmed/28587667
http://dx.doi.org/10.1186/s12933-017-0555-1