The genomic road to invasion—examining the similarities and differences in the genomes of associated oral pre-cancer and cancer samples

BACKGROUND: It is frequently assumed that pre-invasive lesions are simpler precursors of cancer and will contain a limited subset of the genomic changes seen in their associated invasive disease. Driver mutations are thought to occur early, but it is not known how many of these are present in pre-in...

Descripción completa

Detalles Bibliográficos
Autores principales: Wood, Henry M., Daly, Catherine, Chalkley, Rebecca, Senguven, Burcu, Ross, Lisa, Egan, Philip, Chengot, Preetha, Graham, Jennifer, Sethi, Neeraj, Ong, Thian K., MacLennan, Kenneth, Rabbitts, Pamela, Conway, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461742/
https://www.ncbi.nlm.nih.gov/pubmed/28592326
http://dx.doi.org/10.1186/s13073-017-0442-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461742/
https://www.ncbi.nlm.nih.gov/pubmed/28592326
http://dx.doi.org/10.1186/s13073-017-0442-0

Ejemplares similares