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The genomic road to invasion—examining the similarities and differences in the genomes of associated oral pre-cancer and cancer samples
BACKGROUND: It is frequently assumed that pre-invasive lesions are simpler precursors of cancer and will contain a limited subset of the genomic changes seen in their associated invasive disease. Driver mutations are thought to occur early, but it is not known how many of these are present in pre-in...
Autores principales: | Wood, Henry M., Daly, Catherine, Chalkley, Rebecca, Senguven, Burcu, Ross, Lisa, Egan, Philip, Chengot, Preetha, Graham, Jennifer, Sethi, Neeraj, Ong, Thian K., MacLennan, Kenneth, Rabbitts, Pamela, Conway, Caroline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461742/ https://www.ncbi.nlm.nih.gov/pubmed/28592326 http://dx.doi.org/10.1186/s13073-017-0442-0 |
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