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Recommendations for cerebrospinal fluid collection for the analysis by ELISA of neurogranin trunc P75, α-synuclein, and total tau in combination with Aβ(1–42)/Aβ(1–40)

BACKGROUND: The pathophysiology of neurodegeneration is complex. Its diagnosis requires an early identification of sequential changes in several hallmarks in the brains of affected subjects. The presence of brain pathology can be visualized in the cerebrospinal fluid (CSF) by protein profiling. It i...

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Detalles Bibliográficos
Autores principales: Vanderstichele, Hugo, Demeyer, Leentje, Janelidze, Shorena, Coart, Els, Stoops, Erik, Mauroo, Kimberley, Herbst, Victor, François, Cindy, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461747/
https://www.ncbi.nlm.nih.gov/pubmed/28587660
http://dx.doi.org/10.1186/s13195-017-0265-7