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Nitric oxide prevents a pathogen permissive granulocytic inflammation during tuberculosis

Nitric oxide (NO) contributes to protection from tuberculosis (TB). It is generally assumed that this protection is due to direct inhibition of Mycobacterium tuberculosis (Mtb) growth, which prevents subsequent pathological inflammation. In contrast, we report NO primarily protects mice by repressin...

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Detalles Bibliográficos
Autores principales: Mishra, Bibhuti B., Lovewell, Rustin R., Olive, Andrew J, Zhang, Guoliang, Wang, Wenfei, Eugenin, Eliseo, Smith, Clare M, Yao, Jia Phuah, Long, Jarukit E, Dubuke, Michelle L, Palace, Samantha G., Goguen, Jon D., Baker, Richard E., Nambi, Subhalaxmi, Mishra, Rabinarayan, Booty, Matthew G, Baer, Christina E., Shaffer, Scott A, Dartois, Veronique, McCormick, Beth, Chen, Xinchun, Sassetti, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461879/
https://www.ncbi.nlm.nih.gov/pubmed/28504669
http://dx.doi.org/10.1038/nmicrobiol.2017.72